Nonpeptidic Inhibitors of Human Neutrophil Elastase. 7. Design, Synthesis, and in Vitro Activity of a Series of Pyridopyrimidine Trifluoromethyl Ketones-Reference-Cited by-同舟云学术

Nonpeptidic Inhibitors of Human Neutrophil Elastase. 7. Design, Synthesis, and in Vitro Activity of a Series of Pyridopyrimidine Trifluoromethyl Ketones

Published:1996-01-01 Issue:5 Volume:39 Page:1112-1124
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Edwards Philip D.¹,Andisik Donald W.¹,Strimpler Anne M.¹,Gomes Bruce¹,Tuthill Paul A.¹

Affiliation:

1. Departments of Medicinal Chemistry and Pulmonary Pharmacology, ZENECA Pharmaceuticals, A Business Unit of ZENECA Inc., 1800 Concord Pike, P.O. Box 15437, Wilmington, Delaware 19850-5437

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm950684z

Reference41 articles.

1. Bieth, J. G. Elastases: Catalytic and Biological Properties. InRegulation of MatrixAccumulation; Mecham, R. P., Ed.; Academic Press: New York, 1986; pp 217−320.

2. Pulmonary Emphysema and Proteolysis: 1986; Taylor, J. C., Mittman, C., Eds.; Academic Press, Inc. New York, 1987; pp 1−550.

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