Therapeutic Index of Gramicidin S is Strongly Modulated by d-Phenylalanine Analogues at the β-Turn-Reference-Cited by-同舟云学术

Therapeutic Index of Gramicidin S is Strongly Modulated by d-Phenylalanine Analogues at the β-Turn

Published:2009-01-08 Issue:3 Volume:52 Page:664-674
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Solanas Concepción¹,de la Torre Beatriz G.¹,Fernández-Reyes María¹,Santiveri Clara M.¹,Jiménez M. Ángeles¹,Rivas Luis¹,Jiménez Ana I.¹,Andreu David¹,Cativiela Carlos¹

Affiliation:

1. Departamento de Química Orgánica, Instituto de Ciencia de Materiales de Aragón, Universidad de Zaragoza−CSIC, 50009 Zaragoza, Spain, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Dr. Aiguader 88, 08003 Barcelona, Spain, Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain, and Instituto de Química-Física Rocasolano, CSIC, Serrano 119, 28006 Madrid, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800886n

Reference65 articles.

1. Host Defense Peptides and the New Line of Defence Against Multiresistant Infections

2. Gramicidin S and its use in the Treatment of Infected Wounds

3. Gramicidin S is active against both gram-positive and gram-negative bacteria

4. The interaction of the antimicrobial peptide gramicidin S with lipid bilayer model and biological membranes

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