1. Department of Chemistry, University of Toronto, 80 Saint George Street, Toronto M5S 3H6 Canada, Department of Biochemistry, University of Toronto, 1 King’s College Circle, Toronto, M5S 1A8, Canada, and Department of Chemistry, University of Toronto at Mississauga, 3359 Mississauga Road North, Mississauga, Ontario, L5L 1C6, Canada