Identification of a Novel Class of Small-Molecule Antiangiogenic Agents through the Screening of Combinatorial Libraries Which Function by Inhibiting the Binding and Localization of Proteinase MMP2 to Integrin αVβ3-Reference-Cited by-同舟云学术

Identification of a Novel Class of Small-Molecule Antiangiogenic Agents through the Screening of Combinatorial Libraries Which Function by Inhibiting the Binding and Localization of Proteinase MMP2 to Integrin αVβ3

Published:2001-01-26 Issue:7 Volume:123 Page:1280-1288
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Boger Dale L.¹,Goldberg Joel¹,Silletti Steve¹,Kessler Torsten¹,Cheresh David A.¹

Affiliation:

1. Contribution from the Departments of Chemistry, Immunology, and Vascular Biology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja003579%2B

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1. Molecular angiogenesis

2. Angiogenesis in cancer, vascular, rheumatoid and other disease

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4. Controlling the vasculature: Angiogenesis, anti-angiogenesis and vascular targeting of gene therapy

5. Tumor angiogenesis—new drugs on the block

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