Discovery of AMG 853, a CRTH2 and DP Dual Antagonist
Author:
Affiliation:
1. Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ml1002234
Reference24 articles.
1. Recent Progress in Work on PGD2 Antagonists for Drugs Targeting Allergic Diseases
2. Prostaglandin as a Target Molecule for Pharmacotherapy of Allergic Inflammatory Diseases
3. CRTH2 and D-Type Prostanoid Receptor Antagonists as Novel Therapeutic Agents for Inflammatory Diseases
4. The roles of the prostaglandin D2 receptors DP1 and CRTH2 in promoting allergic responses
5. Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases
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