Structure–Activity Relationship (SAR) Development and Discovery of Potent Indole-Based Inhibitors of the Hepatitis C Virus (HCV) NS5B Polymerase-Reference-Cited by-同舟云学术

Structure–Activity Relationship (SAR) Development and Discovery of Potent Indole-Based Inhibitors of the Hepatitis C Virus (HCV) NS5B Polymerase

Published:2012-01-06 Issue:2 Volume:55 Page:754-765
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chen Kevin X.¹,Vibulbhan Bancha¹,Yang Weiying¹,Sannigrahi Mousumi¹,Velazquez Francisco¹,Chan Tin-Yau¹,Venkatraman Srikanth¹,Anilkumar Gopinadhan N.¹,Zeng Qingbei¹,Bennet Frank¹,Jiang Yueheng¹,Lesburg Charles A.²,Duca Jose¹,Pinto Patrick¹,Gavalas Stephen¹,Huang Yuhua¹,Wu Wanli¹,Selyutin Oleg¹,Agrawal Sony¹,Feld Boris¹,Huang Hsueh-Cheng¹,Li Cheng¹,Cheng Kuo-Chi¹,Shih Neng-Yang¹,Kozlowski Joseph A.¹,Rosenblum Stuart B.,Njoroge F. George¹

Affiliation:

1. Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States

2. Drug Design, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201258k

Reference48 articles.

1. The Scientific Challenge of Hepatitis C

2. The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994