Synthesis and Ca2+-Mobilizing Activity of Purine-Modified Mimics of Adenophostin A: A Model for the Adenophostin−Ins(1,4,5)P3 Receptor Interaction-Reference-Cited by-同舟云学术

Synthesis and Ca2+-Mobilizing Activity of Purine-Modified Mimics of Adenophostin A: A Model for the Adenophostin−Ins(1,4,5)P3 Receptor Interaction

Published:2003-10-02 Issue:23 Volume:46 Page:4860-4871
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Rosenberg Heidi J.¹,Riley Andrew M.¹,Laude Alex J.¹,Taylor Colin W.¹,Potter Barry V. L.¹

Affiliation:

1. Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, UK, and Department of Pharmacology, Tennis Court Road, University of Cambridge, Cambridge, CB2 1PD, UK

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030883f

Reference45 articles.

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2. IP3 receptors and their regulation by calmodulin and cytosolic Ca2+

3. New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor

4. Interactions of Inositol 1,4,5-Trisphosphate (IP3) Receptors with Synthetic Poly(ethylene glycol)-linked Dimers of IP3 Suggest Close Spacing of the IP3-binding Sites

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