Design, Synthesis, and Biological Evaluation of Substituted 2-Cyclohexyl-4-phenyl-1H-imidazoles: Potent and Selective Neuropeptide Y Y5-Receptor Antagonists-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of Substituted 2-Cyclohexyl-4-phenyl-1H-imidazoles: Potent and Selective Neuropeptide Y Y5-Receptor Antagonists

Published:2004-03-20 Issue:9 Volume:47 Page:2318-2325
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Blum Charles A.¹,Zheng Xiaozhang¹,De Lombaert Stéphane¹

Affiliation:

1. Neurogen Corporation, 35 Northeast Industrial Road, Branford, Connecticut 06405

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030490g

Reference31 articles.

1. Stanley, B. G. Neuropeptide Y in Multiple Hypothalamic Sites Controls Eating Behavior, Endocrine, and Autonomic Systems for Body Energy Balance.The Biology of Neuropeptide Y and Related Peptides; Humana: Totowa, NJ, 1993; pp 457−509.

2. The Biology of Neuropeptide Y and Related Peptides; Humana Press: Totowa, NJ, 1993.

3. Evidence for neuropeptide Y mediation of eating produced by food deprivation and for a variant of the Y1 receptor mediating this peptide's effect

4. Pharmacological Treatment of Obesity: Therapeutic Strategies

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