β-Gal Gene Expression MRI Reporter in Melanoma Tumor Cells. Design, Synthesis, and in Vitro and in Vivo Testing of a Gd(III) Containing Probe Forming a High Relaxivity, Melanin-Like Structure upon β-Gal Enzymatic Activation-Reference-Cited by-同舟云学术

β-Gal Gene Expression MRI Reporter in Melanoma Tumor Cells. Design, Synthesis, and in Vitro and in Vivo Testing of a Gd(III) Containing Probe Forming a High Relaxivity, Melanin-Like Structure upon β-Gal Enzymatic Activation

Published:2011-11-15 Issue:12 Volume:22 Page:2625-2635
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Arena Francesca¹,Singh Jebasingh Bhagavath¹,Gianolio Eliana¹,Stefanìa Rachele¹,Aime Silvio¹

Affiliation:

1. Centro di Imaging Molecolare, Dipartimento di Chimica IFM, Università degli Studi di Torino, Via Nizza 52, 10126 Torino, Italy

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/bc200486j

Reference25 articles.

1. Genetically Engineered Whole-Cell Sensing Systems: Coupling Biological Recognition with Reporter Genes

2. S-Gal®, A novel 1H MRI reporter for β-galactosidase

3. A“Smart” Magnetic Resonance Imaging Agent That Reports on Specific Enzymatic Activity

4. In vivo visualization of gene expression using magnetic resonance imaging

5. A Gd3+-Based Magnetic Resonance Imaging Contrast Agent Sensitive to β-Galactosidase Activity Utilizing a Receptor-Induced Magnetization Enhancement (RIME) Phenomenon

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