Structural Basis for Inhibitor Specificity in Human Poly(ADP-ribose) Polymerase-3-Reference-Cited by-同舟云学术

Structural Basis for Inhibitor Specificity in Human Poly(ADP-ribose) Polymerase-3

Published:2009-04-08 Issue:9 Volume:52 Page:3108-3111
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lehtiö Lari¹,Jemth Ann-Sofie¹,Collins Ruairi¹,Loseva Olga¹,Johansson Andreas¹,Markova Natalia¹,Hammarström Martin¹,Flores Alex¹,Holmberg-Schiavone Lovisa¹,Weigelt Johan¹,Helleday Thomas¹,Schüler Herwig¹,Karlberg Tobias¹

Affiliation:

1. Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-17177 Stockholm, Sweden. Department of Genetics, Microbiology, and Toxicology, Stockholm University, SE-10691 Stockholm, Sweden. iNovacia AB, SE-11251 Stockholm, Sweden. Gray Institute for Radiation Oncology & Biology, University of Oxford, Oxford OX3 7DQ, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900052j

Reference19 articles.

1. Poly(ADP-ribose). The most elaborate metabolite of NAD+

2. Poly(ADP-ribose): novel functions for an old molecule

3. Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse

4. Role of poly(ADP-ribose) formation in DNA repair

5. Role of Poly(ADP-ribose) polymerase 1 (PARP-1) in Cardiovascular Diseases: The Therapeutic Potential of PARP Inhibitors

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