1. Department of Biotechnology, Tottori University, Tottori 680-8552, Japan, Ohkawara Kakouki Co. Ltd., Yokohama 224-0053, Japan, VTT Biotechnology, P.O. Box 1500 (Tietotie 2), FIN-02044 VTT, Finland, and Department of Chemical Technology, Helsinki University of Technology, P.O. Box 6100 HUT, (Espoo), Finland