Structure and Stability of Duplex DNA Containing (5′S)-5′,8-Cyclo-2′-deoxyadenosine: An Oxidatively Generated Lesion Repaired by NER
Author:
Affiliation:
1. Department of Pharmacological Sciences, School of Medicine, Stony Brook University, Stony Brook, New York 11794-8651, United States
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/tx300193k
Reference56 articles.
1. Oxidatively induced DNA damage: Mechanisms, repair and disease
2. Radiation Chemistry of Nucleotides: 8,5′-Cyclonucleotide Formation and Phosphate Release Initiated by Hydroxyl Radical Attack on Adenosine Monophosphates
3. The oxidatively induced DNA lesions 8,5′-cyclo-2′-deoxyadenosine and 8-hydroxy-2′-deoxyadenosine are strongly resistant to acid-induced hydrolysis of the glycosidic bond
4. Distribution of Damage in Irradiated 5′-AMP: 8,5′-Cyclo-AMP, 8-Hydroxy-AMP, and Adenine Release
5. Stereoselective intramolecular cyclization in irradiated nucleic acids: R- and S-8,5′-cycloadenosine in polyadenylic acid
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