1. Department of Biophysics, University of Maastricht, Department of Radiology, University Hospital Maastricht (azM), Department of Biochemistry, University of Maastricht, Department of Cardiology, University of Maastricht, and Department of Pathology, Electron Microscopy Unit, University of Maastricht, Maastricht, The Netherlands, and Department of Biomedical Engineering, Technische Universiteit Eindhoven, Eindhoven, The Netherlands