Active Sites of Spinoxin, a Potassium Channel Scorpion Toxin, Elucidated by Systematic Alanine Scanning

Author:

Peigneur Steve1,Yamaguchi Yoko2,Kawano Chihiro2,Nose Takeru3,Nirthanan Selvanayagam4,Gopalakrishnakone Ponnampalam5,Tytgat Jan1,Sato Kazuki2

Affiliation:

1. Toxicology and Pharmacology, University of Leuven, Campus Gasthuisberg O&N2, Herestraat 49, P.O. Box 922, Leuven 3000, Belgium

2. Department of Environment Sciences, Fukuoka Women’s University, Fukuoka 813-8529, Japan

3. Faculty of Arts and Science, Kyushu University, Fukuoka, 819-0395, Japan

4. Menzies Health Institute Queensland, Gold Coast, Queensland 4222, Australia

5. Venom and Toxin Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore

Funder

Federaal Wetenschapsbeleid

Fonds Wetenschappelijk Onderzoek

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

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