Oncogenic Mutations in the DNA-Binding Domain of FOXO1 that Disrupt Folding: Quantitative Insights from Experiments and Molecular Simulations-Reference-Cited by-同舟云学术

Oncogenic Mutations in the DNA-Binding Domain of FOXO1 that Disrupt Folding: Quantitative Insights from Experiments and Molecular Simulations

Published:2022-07-27 Issue:16 Volume:61 Page:1669-1682
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Novack Dylan¹,Qian Lei²^ORCID,Acker Gwyneth²,Voelz Vincent A.¹^ORCID,Baxter Richard H. G.²^ORCID

Affiliation:

1. Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, United States

2. Department of Medical Genetics & Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, 3440 North Broad Street, Philadelphia, Pennsylvania 19140, United States

Funder

Army Research Laboratory

National Institute of General Medical Sciences

Division of Computer and Network Systems

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.2c00224

Reference83 articles.

1. The winged-helix DNA-binding motif: Another helix-turn-helix takeoff

2. Forkhead Transcription Factors in Health and Disease

3. Toward a mechanistic understanding of DNA binding by forkhead transcription factors and its perturbation by pathogenic mutations

4. FOXO transcription factors in cancer development and therapy

5. Phosphorylation of the Transcription Factor Forkhead Family Member FKHR by Protein Kinase B

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Markov State Model of Solvent Features Reveals Water Dynamics in Protein-Peptide Binding;The Journal of Physical Chemistry B;2023-12-11

2. Folding@home: Achievements from over 20 years of citizen science herald the exascale era;Biophysical Journal;2023-07