Tuning Enzyme Thermostability via Computationally Guided Covalent Stapling and Structural Basis of Enhanced Stabilization-Reference-Cited by-同舟云学术

Tuning Enzyme Thermostability via Computationally Guided Covalent Stapling and Structural Basis of Enhanced Stabilization

Published:2022-05-25 Issue:11 Volume:61 Page:1041-1054
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Iannuzzelli Jacob A.¹,Bacik John-Paul²^ORCID,Moore Eric J.¹,Shen Zhuofan³,Irving Ellen M.¹^ORCID,Vargas David A.¹,Khare Sagar D.³^ORCID,Ando Nozomi²^ORCID,Fasan Rudi¹^ORCID

Affiliation:

1. Department of Chemistry, University of Rochester, Rochester, New York 14627, United States

2. Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States

3. Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854, United States

Funder

Cornell University

Division of Chemical, Bioengineering, Environmental, and Transport Systems

National Institute of General Medical Sciences

National Science Foundation

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.2c00033

Reference67 articles.

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4. Stability of biocatalysts

5. Engineered enzymes for chemical production

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