Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of <i>Ideonella sakaiensis</i> PETase and Variants with Improved Stability and Activity-Reference-Cited by-同舟云学术

Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of Ideonella sakaiensis PETase and Variants with Improved Stability and Activity

Published:2022-08-11 Issue:2 Volume:62 Page:437-450
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Joho Yvonne¹²,Vongsouthi Vanessa²^ORCID,Spence Matthew A.²,Ton Jennifer²,Gomez Chloe²,Tan Li Lynn²^ORCID,Kaczmarski Joe A.²³,Caputo Alessandro T.¹,Royan Santana¹,Jackson Colin J.²⁴³^ORCID,Ardevol Albert¹⁵

Affiliation:

1. Manufacturing, Commonwealth Scientific and Industrial Research Organisation, Clayton, Victoria 3168, Australia

2. Research School of Chemistry, Australian National University, Canberra, ACT 2601, Australia

3. ARC Centre of Excellence for Innovations in Synthetic Biology, Research School of Chemistry, Australian National University, Canberra, ACT 2601, Australia

4. ARC Centre of Excellence for Innovations in Peptide & Protein Science, Research School of Chemistry, Australian National University, Canberra, ACT 2601, Australia

5. CSIRO Synthetic Biology Future Science Platform, GPO Box 1700, Canberra, ACT 2601, Australia

Funder

Australian Research Council

Commonwealth Scientific and Industrial Research Organisation

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.2c00323

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