New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity-Reference-Cited by-同舟云学术

New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity

Author:

Liu Jian¹,Hiser Carrie²,Li Fei³,Hall Robert⁴,Garavito R. Michael²,Ferguson-Miller Shelagh²^ORCID

Affiliation:

1. Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, United States

2. Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan 48824, United States

3. Amgen Inc., San Francisco, California 94080, United States

4. Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, United States

Funder

National Cancer Institute

National Institutes of Health

National Institute of General Medical Sciences

Argonne National Laboratory

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

Reference73 articles.

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