Targeted Protein Degradation via Lysosomes
Author:
Affiliation:
1. Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, Texas 77030, United States
2. Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, United States
Funder
National Cancer Institute
Baylor College of Medicine
Cancer Prevention and Research Institute of Texas
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.2c00310
Reference131 articles.
1. Cellular proteostasis: degradation of misfolded proteins by lysosomes
2. Intracellular Protein Degradation: From a Vague Idea, through the Lysosome and the Ubiquitin-Proteasome System, and onto Human Diseases and Drug Targeting (Nobel Lecture)
3. Proteasomal and Autophagic Degradation Systems
4. Regulation of proteasome assembly and activity in health and disease
5. Regulated protein degradation
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