Insights into Binding of Single-Stranded Viral RNA Template to the Replication–Transcription Complex of SARS-CoV-2 for the Priming Reaction from Molecular Dynamics Simulations-Reference-Cited by-同舟云学术

Insights into Binding of Single-Stranded Viral RNA Template to the Replication–Transcription Complex of SARS-CoV-2 for the Priming Reaction from Molecular Dynamics Simulations

Published:2022-02-24 Issue:6 Volume:61 Page:424-432
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Wang Jimin¹^ORCID,Shi Yuanjun²,Reiss Krystle²,Allen Brandon²^ORCID,Maschietto Federica²^ORCID,Lolis Elias³^ORCID,Konigsberg William H.¹,Lisi George P.⁴^ORCID,Batista Victor S.²^ORCID

Affiliation:

1. Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520-8114, United States

2. Department of Chemistry, Yale University, New Haven, Connecticut 06511-8499, United States

3. Department of Pharmacology, Yale University, New Haven, Connecticut 06520-8066, United States

4. Department of Molecular and Cell Biology and Biochemistry, Brown University, Providence, Rhode Island 02912, United States

Funder

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.1c00755

Reference57 articles.

1. DNA Primases

2. Mechanism and evolution of DNA primases

3. Continuous and Discontinuous RNA Synthesis in Coronaviruses

4. The structural changes of T7 RNA polymerase from transcription initiation to elongation

5. Stepwise Promoter Melting by Bacterial RNA Polymerase

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