Chemical Editing of Macrocyclic Natural Products and Kinetic Profiling Reveal Slow, Tight-Binding Histone Deacetylase Inhibitors with Picomolar Affinities-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Chemical Editing of Macrocyclic Natural Products and Kinetic Profiling Reveal Slow, Tight-Binding Histone Deacetylase Inhibitors with Picomolar Affinities

Published:2017-09-15 Issue:38 Volume:56 Page:5134-5146
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Kitir Betül¹,Maolanon Alex R.¹,Ohm Ragnhild G.¹,Colaço Ana R.²,Fristrup Peter²^ORCID,Madsen Andreas S.¹,Olsen Christian A.¹^ORCID

Affiliation:

1. Center for Biopharmaceuticals and Department for Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark

2. Department of Chemistry, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark

Funder

K?benhavns Universitet

Carlsbergfondet

H2020 European Research Council

Lundbeckfonden

Novo Nordisk Foundation

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.7b00725

Reference51 articles.

1. Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

2. Acetylation site specificities of lysine deacetylase inhibitors in human cells

3. The many roles of histone deacetylases in development and physiology: implications for disease and therapy

4. Sirtuins as regulators of metabolism and healthspan

5. Molecular Evolution of the Histone Deacetylase Family: Functional Implications of Phylogenetic Analysis

Cited by 26 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide‐Activated Sirtuin 7**;Angewandte Chemie International Edition;2023-11-07

2. Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide‐Activated Sirtuin 7**;Angewandte Chemie;2023-11-07

3. Evolution of Slow-Binding Inhibitors Targeting Histone Deacetylase Isoforms;Journal of Medicinal Chemistry;2023-08-31

4. The Importance of the “Time Factor” for the Evaluation of Inhibition Mechanisms: The Case of Selected HDAC6 Inhibitors;Biology;2023-07-26

5. Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide Activated SIRT7;2023-06-16

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3