Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9

Author:

Maekawa Keiko12,Adachi Motoyasu3,Matsuzawa Yumiko2,Zhang Qinghai4,Kuroki Ryota5,Saito Yoshiro2,Shah Manish B.67ORCID

Affiliation:

1. Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences, Doshisha Women’s College of Liberal Arts, Kodo, Kyotanabe, Kyoto 610-0395, Japan

2. Division of Medicinal Safety Science, National Institute of Health Sciences, Kamiyoga 1-18-1, Setagaya, Tokyo 158-8501, Japan

3. National Institutes for Quantum and Radiological Science and Technology, 2-4 Shirane Shirakata, Tokai-mura, Ibaraki 319-1106, Japan

4. Department of Integrative Structural and Computational Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States

5. Japan Atomic Energy Agency, 2-4 Shirane Shirakata, Tokai-mura, Ibaraki 319-1195, Japan

6. Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06267, United States

7. Department of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, 106 New Scotland Avenue, Albany, New York 12208, United States

Funder

Ministry of Education, Culture, Sports, Science and Technology

U.S. Department of Health and Human Services

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

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