Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody–Carbohydrate Binding Affinity by an Order of Magnitude-Reference-Cited by-同舟云学术

Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody–Carbohydrate Binding Affinity by an Order of Magnitude

Published:2018-12-20 Issue:6 Volume:58 Page:714-726
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Haji-Ghassemi Omid¹,Müller-Loennies Sven²,Brooks Cory L.³,MacKenzie C. Roger⁴,Caveney Nathanael¹,Van Petegem Filip⁵,Brade Lore²,Kosma Paul⁵^ORCID,Brade Helmut²,Evans Stephen V.¹^ORCID

Affiliation:

1. Department of Biochemistry and Microbiology, University of Victoria, P.O. Box 3055 STN CSC, Victoria, British Columbia, Canada V8P 3P6

2. Research Center Borstel, Leibniz Lung Center, Parkallee 22, Borstel D-23845, Germany

3. Department of Chemistry, Fresno State University, 2555 East San Ramon Avenue, MS SB70, Fresno, California 93740, United States

4. Human Health Therapeutics Portfolio, National Research Council Canada, 100 Sussex Drive, Ottawa, Ontario, Canada K1A 0R6

5. Department of Chemistry, University of Natural Resources and Life Sciences, A-1190 Vienna, Austria

Funder

Natural Sciences and Engineering Research Council of Canada

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.8b00318

Reference69 articles.

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2. B lymphocytes: how they develop and function

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4. The Mechanism and Regulation of Chromosomal V(D)J Recombination

5. Antibody Recognition of Chlamydia LPS: Structural Insights of Inherited Immune Responses

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