An Open Library of Human Kinase Domain Constructs for Automated Bacterial Expression

Author:

Albanese Steven K.12,Parton Daniel L.2,Işık Mehtap23,Rodríguez-Laureano Lucelenie2,Hanson Sonya M.2,Behr Julie M.24,Gradia Scott5,Jeans Chris5,Levinson Nicholas M.6,Seeliger Markus A.7,Chodera John D.2ORCID

Affiliation:

1. Louis V. Gerstner, Jr Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States

2. Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States

3. Tri-Institutional PhD Program in Chemical Biology, Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York 10065, United States

4. Tri-Institutional Program in Computational Biology and Medicine, Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York 10065, United States

5. QB3MacroLab, University of California, Berkeley, California 94720, United States

6. Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455, United States

7. Department of Pharmacological Sciences, Stony Brook University Medical School, Stony Brook, New York 11794, United States

Funder

National Cancer Institute

National Institute of General Medical Sciences

Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center

Marie-Jos?e and Henry R. Kravis Center for Molecular Oncology

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Reference52 articles.

1. The Protein Kinase Complement of the Human Genome

2. Hunter, T., and Manning, G. (2015) In Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease (Wheeler, D. L., and Yarden, Y., Eds.) pp 1–15, Springer, New York.

3. Targeting the cancer kinome through polypharmacology

4. American Cancer Society (2015) Cancer Facts & Figures 2015.

5. Will the Ubiquitin System Furnish as Many Drug Targets as Protein Kinases?

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