Conformational Response of N-Terminally Truncated Cytochrome P450 3A4 to Ligand Binding in Solution-Reference-Cited by-同舟云学术

Conformational Response of N-Terminally Truncated Cytochrome P450 3A4 to Ligand Binding in Solution

Published:2019-08-28 Issue:37 Volume:58 Page:3903-3910
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Chuo Shih-Wei¹,Liou Shu-Hao¹²^ORCID,Wang Lee-Ping¹^ORCID,Britt R. David¹^ORCID,Poulos Thomas L.³⁴⁵^ORCID,Sevrioukova Irina F.³^ORCID,Goodin David B.¹^ORCID

Affiliation:

1. Department of Chemistry, University of California, Davis, One Shields Avenue, Davis, California 95616, United States

2. Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, United States

3. Department of Molecular Biology and Biochemistry, University of California, Irvine, California 92697-3900, United States

4. Department of Chemistry, University of California, Irvine, California 92697-3900, United States

5. Department of Pharmaceutical Sciences, University of California, Irvine, California 92697-3900, United States

Funder

National Institute of Environmental Health Sciences

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.9b00620

Reference37 articles.

1. CYTOCHROME P-450 3A4: Regulation and Role in Drug Metabolism

2. Interactions of cytochrome P450s with their ligands

3. A thermodynamic model of regulation: modulation of redox equilibria in camphor monoxygenase.

4. Coupling of spin, substrate, and redox equilibriums in cytochrome P450

5. Effector Roles of Putidaredoxin on Cytochrome P450cam Conformational States

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