Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2
Author:
Affiliation:
1. Department of Chemistry, The University of Iowa, Iowa City, Iowa 52242, United States
Funder
Division of Chemistry
National Institute of General Medical Sciences
College of Liberal Arts and Sciences, University of Iowa
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.9b00349
Reference50 articles.
1. Cancer metabolism meets systems biology: Pyruvate kinase isoform PKM2 is a metabolic master regulator
2. Pyruvate kinase M2 and cancer: an updated assessment
3. The M1- and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing.
4. PKM2 contributes to cancer metabolism
5. Structural Basis for Tumor Pyruvate Kinase M2 Allosteric Regulation and Catalysis,
Cited by 12 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Deciphering the interaction between PKM2 and the built-in thermodynamic properties of the glycolytic pathway in cancer cells;Journal of Biological Chemistry;2024-09
2. The role of PKM2 in cancer progression and its structural and biological basis;Journal of Physiology and Biochemistry;2024-02-08
3. Development of isoselenazolium chlorides as selective pyruvate kinase isoform M2 inhibitors;European Journal of Medicinal Chemistry;2023-09
4. Identification of residues involved in allosteric signal transmission from amino acid binding site of pyruvate kinase muscle isoform 2;PLOS ONE;2023-03-10
5. Unexpected alkyl isomerization at the silicon ligand of an unsaturated Rh complex: combined experiment and theory;Dalton Transactions;2023
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3