Probing the Impact of Local Structural Dynamics of Conformational Epitopes on Antibody Recognition
Author:
Affiliation:
1. Department of Medicinal Chemistry, University of Washington, Seattle, Washington 98195, United States
2. Department of Pharmaceutics, University of Washington, Seattle, Washington 98195, United States
Funder
National Center for Research Resources
National Institute of Allergy and Infectious Diseases
Bill and Melinda Gates Foundation
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.5b01354
Reference96 articles.
1. Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design
2. Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies
3. Correlation between segmental mobility and the location of antigenic determinants in proteins
4. Folding and binding cascades: Dynamic landscapes and population shifts
5. ElliPro: a new structure-based tool for the prediction of antibody epitopes
Cited by 24 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A Novel PNGase Rc for Improved Protein N-Deglycosylation in Bioanalytics and Hydrogen–Deuterium Exchange Coupled With Mass Spectrometry Epitope Mapping under Challenging Conditions;Analytical Chemistry;2022-06-24
2. Structural dynamics reveal isolate-specific differences at neutralization epitopes on HIV Env;iScience;2022-06
3. A novel PNGase Rc for improved protein N-deglycosylation in bioanalytics and HDX-MS epitope mapping under challenging conditions;2022-04-13
4. Epitope alteration by small molecules and applications in drug discovery;Chemical Science;2022
5. Epitope-imprinted polymers: Design principles of synthetic binding partners for natural biomacromolecules;Science Advances;2021-10-29
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3