Production and Release of Proinflammatory Mediators by the Cockroach Allergen Bla g 1 via a Shared Membrane-Destabilization Mechanism-Reference-Cited by-同舟云学术

Production and Release of Proinflammatory Mediators by the Cockroach Allergen Bla g 1 via a Shared Membrane-Destabilization Mechanism

Published:2024-06-25 Issue:14 Volume:63 Page:1730-1737
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Foo Alexander C.Y.¹^ORCID,Edin Matthew L.²,Lin Wan-Chi²,Lih Fred B.³,Gabel Scott A.⁴,Uddin Mohammad N.²,Fessler Michael B.²,Zeldin Darryl C.²,Mueller Geoffrey A.⁴^ORCID

Affiliation:

1. Dept. of Chemistry, St. Francis Xavier University, Antigonish, Nova Scotia B2G 2W5, Canada

2. Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Science, Research Triangle Park, North Carolina 27709, United States

3. Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Science, Research Triangle Park, North Carolina 27709, United States

4. Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Science, Research Triangle Park, North Carolina 27709, United States

Funder

National Institute of Environmental Health Sciences

Natural Sciences and Engineering Research Council of Canada

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.3c00631

Reference35 articles.

1. Allergens are distributed into few protein families and possess a restricted number of biochemical functions

2. The novel structure of the cockroach allergen Bla g 1 has implications for allergenicity and exposure assessment

3. Hydrophobic ligands influence the structure, stability, and processing of the major cockroach allergen Bla g 1

4. The mosquito protein AEG12 displays both cytolytic and antiviral properties via a common lipid transfer mechanism

5. Expanding the antiviral potential of the mosquito lipid‐transfer protein AEG12 against SARS‐CoV ‐2 using hydrophobic antiviral ligands