Kinetic and Structural Characterization of <i>Trypanosoma cruzi</i> Hypoxanthine–Guanine–Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors-Reference-Cited by-同舟云学术

Kinetic and Structural Characterization of Trypanosoma cruzi Hypoxanthine–Guanine–Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors

Published:2023-07-07 Issue:14 Volume:62 Page:2182-2201
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Glockzin Kayla¹^ORCID,Meneely Kathleen M.²^ORCID,Hughes Ryan¹,Maatouk Sean W.¹^ORCID,Piña Grace E.¹^ORCID,Suthagar Kajitha³,Clinch Keith³,Buckler Joshua N.³^ORCID,Lamb Audrey L.²^ORCID,Tyler Peter C.³^ORCID,Meek Thomas D.¹,Katzfuss Ardala¹^ORCID

Affiliation:

1. Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States

2. Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States

3. Ferrier Research Institute, Victoria University of Wellington, Gracefield Research Centre, 69 Gracefield Road, Gracefield, Lower Hutt 5010, New Zealand

Funder

Division of Chemistry

National Institute of Allergy and Infectious Diseases

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.3c00116

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4. An Estimate of the Burden of Chagas Disease in the United States

5. Texas Department of State Health and Services. Chagas disease data. 2022. https://www.dshs.state.tx.us/IDCU/disease/chagas/Chagas-Disease-Data.aspx (accessed May 9, 2022).