4-Oxo-2-nonenal-Induced α-Synuclein Oligomers Interact with Membranes in the Cell, Leading to Mitochondrial Fragmentation-Reference-Cited by-同舟云学术

4-Oxo-2-nonenal-Induced α-Synuclein Oligomers Interact with Membranes in the Cell, Leading to Mitochondrial Fragmentation

Published:2023-07-24 Issue:16 Volume:62 Page:2417-2425
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Andersen Camilla B.¹²,Lausdahl Astrid K.²,Nielsen Janni¹,Clausen Mathias P.²,Mulder Frans A. A.¹³^ORCID,Otzen Daniel E.¹⁴^ORCID,Arnspang Eva C.²^ORCID

Affiliation:

1. Interdisciplinary Nanoscience Center (iNANO), Gustav Wieds Vej 14, Aarhus University, 8000 Aarhus C, Denmark

2. Department of Green Technology, SDU-Biotechnology, University of Southern Denmark, 5230 Odense, Denmark

3. Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark

4. Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark

Funder

Grosserer L. F. Foghts Fond

Danmarks Frie Forskningsfond

Villum Fonden

Lundbeckfonden

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.3c00114

Reference50 articles.

1. -Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies

2. α‐synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities

3. Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

4. In vivo demonstration that -synuclein oligomers are toxic

5. The N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranes

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Poration of mitochondrial membranes by amyloidogenic peptides and other biological toxins;Journal of Neurochemistry;2024-08-30

2. Molecular properties and diagnostic potential of monoclonal antibodies targeting cytotoxic α-synuclein oligomers;npj Parkinson's Disease;2024-07-29

3. 4-Oxo-2-Nonenal- and Agitation-Induced Aggregates of α-Synuclein and Phosphorylated α-Synuclein with Distinct Biophysical Properties and Biomedical Applications;Cells;2024-04-24