Noncompetitive Allosteric Antagonism of Death Receptor 5 by a Synthetic Affibody Ligand

Author:

Vunnam Nagamani1,Szymonski Sophia1,Hirsova Petra2,Gores Gregory J.2,Sachs Jonathan N.1ORCID,Hackel Benjamin J.3ORCID

Affiliation:

1. Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States

2. Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, United States

3. Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, Minnesota 55455, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

National Institute of Allergy and Infectious Diseases

National Institute of Biomedical Imaging and Bioengineering

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

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