Cholesterol Asymmetrically Modulates the Conformational Ensemble of the Nucleotide-Binding Domains of P-Glycoprotein in Lipid Nanodiscs
Author:
Affiliation:
1. Department of Medicinal Chemistry, University of Washington, Seattle, Washington 98195-7610, United States
2. Department of Biological Sciences, MARC Program, California State University, Fullerton, California 92834-6850, United States
Funder
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.0c00824
Reference41 articles.
1. Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.
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4. Energy transduction and alternating access of the mammalian ABC transporter P-glycoprotein
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