Mechanistic Insight into Lipid Binding to Yeast Niemann Pick Type C2 Protein-Reference-Cited by-同舟云学术

Mechanistic Insight into Lipid Binding to Yeast Niemann Pick Type C2 Protein

Published:2020-11-03 Issue:45 Volume:59 Page:4407-4420
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Moesgaard Laust¹,Petersen Daniel²,Szomek Maria²,Reinholdt Peter¹^ORCID,Winkler Mikael B. L.³,Frain Kelly May³,Müller Peter⁴,Pedersen Bjørn Panyella³,Kongsted Jacob¹^ORCID,Wüstner Daniel²^ORCID

Affiliation:

1. Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark

2. Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark

3. Department of Molecular Biology and Genetics, Aarhus University, Gustav Wieds Vej 10, Aarhus C 8000, Denmark

4. Department of Biology, Humboldt University Berlin, Unter den Linden 6, 10099 Berlin, Germany

Funder

Natur og Univers, Det Frie Forskningsr?d

Carlsbergfondet

H2020 European Research Council

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.0c00574

Reference51 articles.

1. How cholesterol interacts with proteins and lipids during its intracellular transport

2. NPC intracellular cholesterol transporter 1 (NPC1)-mediated cholesterol export from lysosomes

3. Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease

4. Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease

5. NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

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