Legumain-Triggered Macrocyclization of Radiofluorinated Tracer for Enhanced PET Imaging
Author:
Affiliation:
1. School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China
2. NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, PR China
Funder
National Natural Science Foundation of China
Jiangsu Commission of Health
Publisher
American Chemical Society (ACS)
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.4c00128
Reference37 articles.
1. An Overview of Targeting Legumain for Inhibiting Cancers
2. Role of LGMN in tumor development and its progression and connection with the tumor microenvironment
3. Enzyme-Agnostic Lysosomal Screen Identifies New Legumain-Cleavable ADC Linkers
4. A protease‐responsive fluorescent probe for sensitive imaging of legumain activity in living tumor cells
5. Dual-responsive self-assembly in lysosomes enables cell cycle arrest for locking glioma cell growth
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