Structural Optimization of Decoy Oligonucleotide-Based PROTAC That Degrades the Estrogen Receptor-Reference-Cited by-同舟云学术

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Structural Optimization of Decoy Oligonucleotide-Based PROTAC That Degrades the Estrogen Receptor

Published:2023-09-22 Issue:10 Volume:34 Page:1780-1788
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Naganuma Miyako¹²,Ohoka Nobumichi³^ORCID,Tsuji Genichiro¹^ORCID,Inoue Takao³,Naito Mikihiko⁴^ORCID,Demizu Yosuke¹²^ORCID

Affiliation:

1. Division of Organic Chemistry, National Institute of Health Sciences, Kanagawa 210-9501, Japan

2. Graduate School of Medical Life Science, Yokohama City University, Kanagawa 236-0027, Japan

3. Division of Molecular Target and Gene Therapy Products, National Institute of Health Sciences, Kanagawa 210-9501, Japan

4. Laboratory of Targeted Protein Degradation, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 110-0033, Japan

Funder

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.3c00332

Reference26 articles.

1. PROTAC targeted protein degraders: the past is prologue

2. Recent Developments in PROTAC‐Mediated Protein Degradation: From Bench to Clinic

3. Proteolysis targeting chimera (PROTAC) in drug discovery paradigm: Recent progress and future challenges

4. PROTACs: great opportunities for academia and industry (an update from 2020 to 2021)

5. Aptamer-Based Targeted Protein Degradation

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