Reversible Chemical Modification of Antibody Effector Function Mitigates Unwanted Systemic Immune Activation-Reference-Cited by-同舟云学术

Reversible Chemical Modification of Antibody Effector Function Mitigates Unwanted Systemic Immune Activation

Published:2024-05-24 Issue:6 Volume:35 Page:855-866
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Moquist Philip N.¹,Zhang Xinqun²,Leiske Chris I.²,Eng-Duncan Nicole M.-L.¹,Zeng Weiping³,Bindman Noah A.²,Wo Serena W.²,Wong Abbie⁴,Henderson Clark M.⁴,Crowder Karalyne⁵,Lyon Robert²,Doronina Svetlana O.¹,Senter Peter D.¹,Neff-LaFord Haley D.⁵,Sussman Django²,Gardai Shyra J.⁶,Levengood Matthew R.²^ORCID

Affiliation:

1. ADC Chemistry, Pfizer, Inc., 21823 30th Dr. SE, Bothell, Washington 98021, United states

2. ADC Antibody Engineering, Pfizer, Inc., 21823 30th Dr. SE, Bothell, Washington 98021, United States

3. ADC In Vivo Pharmacology, Pfizer, Inc., 21823 30th Dr. SE, Bothell, Washington 98021, United States

4. ADC Translational Sciences, Pfizer, Inc., 21823 30th Dr. SE, Bothell, Washington 98021, United States

5. Non-Clinical Sciences, Pfizer, Inc., 21823 30th Dr. SE, Bothell, Washington 98021, United States

6. Immunology, Pfizer, Inc., 21823 30th Dr. SE, Bothell, Washington 98021, United States

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.4c00212

Reference70 articles.

1. Fcγ receptors as regulators of immune responses

2. Immune Inhibitory Receptors

3. Understanding Fc Receptor Involvement in Inflammatory Diseases: From Mechanisms to New Therapeutic Tools

4. From CD16a Biology to Antibody-Dependent Cell-Mediated Cytotoxicity Improvement

5. A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer