Synthesis and Biological Evaluation of a Carbamate-Containing Tubulysin Antibody

Synthesis and Biological Evaluation of a Carbamate-Containing Tubulysin Antibody–Drug Conjugate

Published:2020-09-03 Issue:10 Volume:31 Page:2350-2361
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Cheng Heng¹^ORCID,Cong Qiang¹,Dervin Dan²,Stevens Alice²,Vemuri Kavitha²,Huber Mary²,Juliano Jennifer²,Cuison Severino²,Sung Janette²,Passmore David²,Chong Colin³,Greenbaum Meghan³,Kwok Eilene³,Jiang Jerry³,Pan Chin³,Rao-Naik Chetana²,Rangan Vangipuram²,Kempe Tom²,Tatum Andrea²,Deshpande Shrikant²,Cardarelli Pina³,Vite Gregory⁴,Gangwar Sanjeev¹

Affiliation:

1. Discovery Chemistry, Bristol Myers Squibb, 700 Bay Road, Redwood City, California 94063, United States

2. Protein Chemistry, Bristol Myers Squibb, 700 Bay Road, Redwood City, California 94063, United States

3. Pharmacology, Bristol Myers Squibb, 700 Bay Road, Redwood City, California 94063, United States

4. Discovery Chemistry, Bristol Myers Squibb, 3551 Lawrenceville Road, Princeton, New Jersey 08540, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.0c00429

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