Pharmacokinetic and Pharmacodynamic Profiles of Glyco-Modified Atrial Natriuretic Peptide Derivatives Synthesized Using Chemo-enzymatic Synthesis Approaches
Author:
Affiliation:
1. Daiichi Sankyo Co., Ltd., 1-2-58, Hiromachi, Sinagawa-ku, Tokyo 140-8710, Japan
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.8b00427
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3. Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells
4. Transcriptome analysis reveals a role for the endothelial ANP-GC-A signaling in interfering with pre-metastatic niche formation by solid cancers
5. ANP is cleared much faster than BNP in patients with congestive heart failure
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