Targeted Antibacterial Activity Guided by Bacteria-Specific Nitroreductase Catalytic Activation to Produce Ciprofloxacin
Author:
Affiliation:
1. Department of Chemistry, Indian Institute of Science Education and Research Pune, Dr. Homi Bhabha Road, Pune-411 008, Maharashtra, India
2. Division of Microbiology, CSIR-Central Drug Research Institute, Lucknow-226031, Uttar Pradesh, India
Funder
Council of Scientific and Industrial Research
Department of Biotechnology , Ministry of Science and Technology
Department of Science and Technology, Ministry of Science and Technology
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.8b00887
Reference62 articles.
1. Global increase and geographic convergence in antibiotic consumption between 2000 and 2015
2. Risks associated with the therapeutic use of fluoroquinolones
3. Ciprofloxacin Affects Host Cells by Suppressing Expression of the Endogenous Antimicrobial Peptides Cathelicidins and Beta-Defensin-3 in Colon Epithelia
4. Nonantibiotic Effects of Fluoroquinolones in Mammalian Cells
5. Syntheses and Antibacterial Activity of N-Acylated Ciprofloxacin Derivatives Based on the Trimethyl Lock
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