High-Throughput Assay for Measuring Monoclonal Antibody Self-Association and Aggregation in Serum-Reference-Cited by-同舟云学术

High-Throughput Assay for Measuring Monoclonal Antibody Self-Association and Aggregation in Serum

Published:2015-03-06 Issue:3 Volume:26 Page:520-528
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Li Xiaoning¹,Geng Steven B.¹,Chiu Mark L.²,Saro Dorina²,Tessier Peter M.¹

Affiliation:

1. Center for Biotechnology & Interdisciplinary Studies, Isermann Department of Chemical & Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York 12180, United States

2. Biologics Research, Biotechnology Center of Excellence, Janssen Research & Development L.L.C., Spring House, Pennsylvania 19477, United States

Funder

Janssen Research & Development, LLC

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.5b00010

Reference43 articles.

1. Antibody Therapeutics in Cancer

2. Monoclonal antibody therapeutics: history and future

3. Engineering Aggregation-Resistant Antibodies

4. Antibody Structure, Instability, and Formulation

5. Improving Monoclonal Antibody Selection and Engineering using Measurements of Colloidal Protein Interactions

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Phase 1 trial evaluating safety and pharmacokinetics of HIV-1 broadly neutralizing mAbs 10E8VLS and VRC07-523LS;JCI Insight;2024-04-08

2. Utility of High Resolution 2D NMR Fingerprinting in Assessing Viscosity of Therapeutic Monoclonal Antibodies;Pharmaceutical Research;2022-02-16

3. Discovery-stage identification of drug-like antibodies using emerging experimental and computational methods;mAbs;2021-01-01

4. Considerations for the Design of Antibody-Based Therapeutics;Journal of Pharmaceutical Sciences;2020-01

5. Net charge of antibody complementarity-determining regions is a key predictor of specificity;Protein Engineering, Design and Selection;2018-11-01