Allosteric Activation of Cytochrome P450 3A4 via Progesterone Bioconjugation
Author:
Affiliation:
1. Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, Canada H3A 0B8
Funder
Fonds de Recherche du Québec - Nature et Technologies
Natural Sciences and Engineering Research Council of Canada
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.6b00604
Reference51 articles.
1. CYTOCHROME P-450 3A4: Regulation and Role in Drug Metabolism
2. UCSF Chimera?A visualization system for exploratory research and analysis
3. Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and Progesterone
4. Cooperativity in Cytochrome P450 3A4
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