New Bifunctional Chelators Incorporating Dibromomaleimide Groups for Radiolabeling of Antibodies with Positron Emission Tomography Imaging Radioisotopes-Reference-Cited by-同舟云学术

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New Bifunctional Chelators Incorporating Dibromomaleimide Groups for Radiolabeling of Antibodies with Positron Emission Tomography Imaging Radioisotopes

Published:2021-03-16 Issue:7 Volume:32 Page:1214-1222
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Farleigh Matthew¹,Pham Truc Thuy¹,Yu Zilin¹,Kim Jana¹,Sunassee Kavitha¹,Firth George¹,Forte Nafsika²^ORCID,Chudasama Vijay²^ORCID,Baker James R.²^ORCID,Long Nicholas J.³^ORCID,Rivas Charlotte¹,Ma Michelle T.¹^ORCID

Affiliation:

1. School of Biomedical Engineering and Imaging Sciences, King’s College London, St. Thomas’ Hospital, London SE1 7EH, U.K.

2. Department of Chemistry, University College London, 20 Gordon Street, London WC1H 0AJ, U.K.

3. Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London W12 0BZ, U.K.

Funder

Engineering and Physical Sciences Research Council

British Heart Foundation

Wellcome Trust

Cancer Research UK

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.0c00710

Reference50 articles.

1. 89Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer

2. Bioconjugates of Chelators with Peptides and Proteins in Nuclear Medicine: Historical Importance, Current Innovations, and Future Challenges

3. Comparison of 64Cu-Complexing Bifunctional Chelators for Radioimmunoconjugation: Labeling Efficiency, Specific Activity, and in Vitro/in Vivo Stability

4. Conjugation and radiolabeling of monoclonal antibodies with zirconium-89 for PET imaging using the bifunctional chelate p-isothiocyanatobenzyl-desferrioxamine

5. Site-specific chelator-antibody conjugation for PET and SPECT imaging with radiometals

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