Phospholipidic Colchicinoids as Promising Prodrugs Incorporated into Enzyme-Responsive Liposomes: Chemical, Biophysical, and Enzymological Aspects

Author:

Shchegravina Ekaterina S.12,Tretiakova Daria S.2,Alekseeva Anna S.2,Galimzyanov Timur R.34,Utkin Yuri N.2,Ermakov Yuri A.3,Svirshchevskaya Elena V.2,Negrebetsky Vadim V.5,Karpechenko Natalia Yu.6,Chernikov Valery P.7,Onishchenko Natalia R.2,Vodovozova Elena L.2,Fedorov Alexey Yu.1,Boldyrev Ivan A.2ORCID

Affiliation:

1. Lobachevsky State University of Niznhy Novgorod, 23 Gagarin Prospest, Nizhny Novgorod, 603950 Russian Federation

2. Shemyakin−Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya Street, Moscow, 117997 Russian Federation

3. A. N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, 31/4 Leninskii Prospekt, Moscow, 119071 Russian Federation

4. National University of Science and Technology MISiS, 4 Leninskiy Prospekt, Moscow, 119049 Russian Federation

5. Pirogov Russian National Research Medical University, 1 Ostrovityanov Street, Moscow, 117997 Russian Federation

6. N. N. Blokhin National Medical Research Center of Oncology, 24 Kashirskoye Shosse, Moscow, 115478 Russian Federation

7. Scientific Research Institute of Human Morphology, 3 Tsurupa Street, Moscow, 117418 Russian Federation

Funder

Russian Science Foundation

Russian Foundation for Basic Research

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

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