Kinetic Solvent Isotope Effect in Human P450 CYP17A1-Mediated Androgen Formation: Evidence for a Reactive Peroxoanion Intermediate
Author:
Affiliation:
1. Department of Biochemistry, University of Illinois at Urbana−Champaign, Urbana, Illinois 61801, United States
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja4086403
Reference22 articles.
1. The Carbon Monoxide-binding Pigment of Liver Microsomes
2. Structure and Chemistry of Cytochrome P450
3. High-valent iron in chemical and biological oxidations
4. Resonance Raman Characterization of the Peroxo and Hydroperoxo Intermediates in Cytochrome P450
Cited by 67 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Optical annealing of peroxo-ferric intermediates in CYP17A1 and product formation.;Journal of Inorganic Biochemistry;2024-11
2. Updates on Mechanisms of Cytochrome P450 Catalysis of Complex Steroid Oxidations;International Journal of Molecular Sciences;2024-08-20
3. Cryoradiolysis of oxygenated cytochrome P450 17A1 with lyase substrates generates expected products;Journal of Inorganic Biochemistry;2024-08
4. Selective α-Hydroxyketone Formation and Subsequent C–C Bond Cleavage by Cytochrome P450 Monooxygenase Enzymes;ACS Catalysis;2024-05-28
5. Oxygen-18 Labeling Defines a Ferric Peroxide (Compound 0) Mechanism in the Oxidative Deformylation of Aldehydes by Cytochrome P450 2B4;ACS Catalysis;2024-01-31
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3