Two Prodrugs of Potent and Selective GluR5 Kainate Receptor Antagonists Actives in Three Animal Models of Pain-Reference-Cited by-同舟云学术

Two Prodrugs of Potent and Selective GluR5 Kainate Receptor Antagonists Actives in Three Animal Models of Pain

Published:2005-05-21 Issue:13 Volume:48 Page:4200-4203
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Dominguez Esteban¹,Iyengar Smriti¹,Shannon Harlan E.¹,Bleakman David¹,Alt Andrew¹,Arnold Brian M.¹,Bell Michael G.¹,Bleisch Thomas J.¹,Buckmaster Jennifer L.¹,Castano Ana M.¹,Del Prado Miriam¹,Escribano Ana¹,Filla Sandra A.¹,Ho Ken H.¹,Hudziak Kevin J.¹,Jones Carrie K.¹,Martinez-Perez Jose A.¹,Mateo Ana¹,Mathes Brian M.¹,Mattiuz Edward L.¹,Ogden Ann Marie L.¹,Simmons Rosa Maria A.¹,Stack Douglas R.¹,Stratford Robert E.¹,Winter Mark A.¹,Wu Zhipei¹,Ornstein Paul L.¹

Affiliation:

1. Centro de Investigación Lilly, S. A. Avda. De la Industria 30, 28108-Alcobendas, Madrid, Spain, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, and Allelix Biopharmaceuticals, Mississauga, Ontario L4V1P1, Canada

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0491952

Reference26 articles.

1. Metabotropic glutamate receptors in brain function and pathology

2. Neuropharmacology of AMPA and kainate receptors

3. Cloned Glutamate Receptors

4. The TINS/TiPS Lecture the molecular biology of mammalian glutamate receptor channels

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