gem-Difluorination of Aminoalkynes via Highly Reactive Dicationic Species in Superacid HF−SbF5: Application to the Efficient Synthesis of Difluorinated Cinchona Alkaloid Derivatives
Author:
Affiliation:
1. Laboratoire “Synthèse et Réactivité des Substances Naturelles”, University of Poitiers, CNRS, 40 Avenue du Recteur Pineau, F-86022 Poitiers Cedex, France brigitte.renoux@univ-poitiers.fr
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo702441p
Reference41 articles.
1. Fluorine substituent effects (on bioactivity)
2. Functionalization of a non activated CH bond: Fluorination of vindoline at C-20 in superacids
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