Synthesis, Ex Vivo Evaluation, and Radiolabeling of Potent 1,5-Diphenylpyrrolidin-2-one Cannabinoid Subtype-1 Receptor Ligands as Candidates for In Vivo Imaging-Reference-Cited by-同舟云学术

Synthesis, Ex Vivo Evaluation, and Radiolabeling of Potent 1,5-Diphenylpyrrolidin-2-one Cannabinoid Subtype-1 Receptor Ligands as Candidates for In Vivo Imaging

Published:2008-08-23 Issue:18 Volume:51 Page:5833-5842
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Donohue Sean R.¹,Krushinski Joseph H.¹,Pike Victor W.¹,Chernet Eyassu¹,Phebus Lee¹,Chesterfield Amy K.¹,Felder Christian C.¹,Halldin Christer¹,Schaus John M.¹

Affiliation:

1. Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, Karolinska Institutet, Department of Clinical Neuroscience, Psychiatry Section, Karolinska Hospital, S-17176 Stockholm, Sweden, and Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800416m

Reference42 articles.

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4. Johnson, M. R.; Melvin, L. S.Cannabinoids as Therapeutic Agents,CRC Press:Boca Raton, FL,1986; pp121−145.

5. Structure of a cannabinoid receptor and functional expression of the cloned cDNA

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