NMR Screening Applied to the Fragment-Based Generation of Inhibitors of Creatine Kinase Exploiting a New Interaction Proximate to the ATP Binding Site-Reference-Cited by-同舟云学术

NMR Screening Applied to the Fragment-Based Generation of Inhibitors of Creatine Kinase Exploiting a New Interaction Proximate to the ATP Binding Site

Published:2007-03-22 Issue:8 Volume:50 Page:1865-1875
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bretonnet Anne-Sophie¹,Jochum Anne¹,Walker Olivier¹,Krimm Isabelle¹,Goekjian Peter¹,Marcillat Olivier¹,Lancelin Jean-Marc¹

Affiliation:

1. Laboratoire de RMN et Spectrométrie de Masse Biomoléculaires, Université Claude Bernard Lyon 1, UMR CNRS 5180 Sciences Analytiques, ESCPE Lyon, Laboratoire de Chimie Organique II-Glycochimie, Université Claude Bernard Lyon 1, UMR CNRS 5181 Méthodologie de Synthèse et Molécules Bio-Actives, ESCPE Lyon, and Biomembranes et Enzymes Associés, UMR CNRS 5246, Université Claude Bernard Lyon 1, 69622 Villeurbanne, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm061460r

Reference56 articles.

1. Organic Chemistry in Drug Discovery

2. Applications of SHAPES Screening in Drug Discovery

3. Discovering High-Affinity Ligands for Proteins: SAR by NMR

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