Improved Peptide Prodrugs of 5-ALA for PDT: Rationalization of Cellular Accumulation and Protoporphyrin IX Production by Direct Determination of Cellular Prodrug Uptake and Prodrug Metabolization-Reference-Cited by-同舟云学术

Improved Peptide Prodrugs of 5-ALA for PDT: Rationalization of Cellular Accumulation and Protoporphyrin IX Production by Direct Determination of Cellular Prodrug Uptake and Prodrug Metabolization

Published:2009-06-03 Issue:13 Volume:52 Page:4026-4037
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Giuntini Francesca¹,Bourré Ludovic¹,MacRobert Alexander J.¹,Wilson Michael¹,Eggleston Ian M.¹

Affiliation:

1. Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, U.K., National Medical Laser Centre, Division of Surgical and Interventional Sciences, UCL Medical School, University College London, London W1W 7EJ, U.K., Division of Microbial Diseases, UCL Eastman Dental Institute, University College London, London WC1X 8LD, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900224r

Reference53 articles.

1. ALA and its clinical impact, from bench to bedside

2. 5-Aminolevulinic Acid-Based Photodynamic Therapy: Principles and Experimental Research

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5. The present and future role of photodynamic therapy in cancer treatment

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