Cell-Based Medicinal Chemistry Optimization of High-Throughput Screening (HTS) Hits for Orally Active Antimalarials. Part 1: Challenges in Potency and Absorption, Distribution, Metabolism, Excretion/Pharmacokinetics (ADME/PK)-Reference-Cited by-同舟云学术

Cell-Based Medicinal Chemistry Optimization of High-Throughput Screening (HTS) Hits for Orally Active Antimalarials. Part 1: Challenges in Potency and Absorption, Distribution, Metabolism, Excretion/Pharmacokinetics (ADME/PK)

Published:2013-09-13 Issue:20 Volume:56 Page:7741-7749
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chatterjee Arnab K.¹

Affiliation:

1. Calibr, 11119 North Torrey Pines Road, Suite 100, San Diego, California 92037, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400314m

Reference39 articles.

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3. Global Phenotypic Screening for Antimalarials

4. 4(1H)-Quinolones. 2. Antimalarial effect of some 2-methyl-3-(1-alkenyl- or -3-alkyl-4(1H)-quinolones

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